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Provider-prescribed treatments. Subject to medical evaluation. Medications are dispensed by licensed U.S. pharmacies.

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GLP-1 University

GLP-1 Program Education

Master everything about semaglutide, tirzepatide, and emerging GLP-1 therapies — including how they work, who may benefit, contraindications, and provider review requirements.

What It Is

Semaglutide is a GLP-1 receptor agonist — a class of medication that mimics the body's natural gut hormone (GLP-1) to regulate appetite, blood sugar, and digestion.

How It Works

By activating GLP-1 receptors in the brain and gut, semaglutide reduces hunger signals, slows gastric emptying, and improves insulin sensitivity. The result is a lower caloric intake and improved metabolic function without requiring willpower alone.

Expected Results

Patients may experience meaningful weight reduction over the course of supervised treatment. Individual results vary based on adherence, lifestyle, starting weight, and medical factors.

Benefits

  • Appetite suppression without stimulants
  • Improved blood sugar regulation
  • Reduced cravings and food noise
  • Provider-supervised dose titration
  • Convenient weekly self-administration
  • No insurance required

Possible Side Effects

  • Nausea (most common, typically improves over time)
  • Constipation or changes in bowel habits
  • Fatigue during dose escalation
  • Injection site reactions (mild)
  • Rare: vomiting, diarrhea

Good Candidate

  • BMI ≥ 30, or BMI ≥ 27 with a weight-related health condition
  • Has attempted lifestyle modifications without adequate results
  • Motivated to follow a supervised program
  • Not contraindicated by medical history
  • Adult age (18+), non-pregnant

Not a Candidate

  • Personal or family history of medullary thyroid carcinoma (MTC)
  • Multiple endocrine neoplasia syndrome type 2 (MEN 2)
  • Currently pregnant or breastfeeding
  • History of pancreatitis (requires additional review)
  • Severe gastrointestinal disease
  • Type 1 diabetes (separate protocols required)

⚠️ Absolute Contraindications

  • MTC or MEN 2 history
  • Pregnancy
  • Known hypersensitivity to semaglutide
  • Severe gastroparesis

Expected Timeline

Many patients begin experiencing appetite changes within the first 1–4 weeks. Meaningful weight changes typically become apparent over the course of several months of consistent use under provider supervision.

Frequently Asked Questions

Is semaglutide the same as Ozempic?

Ozempic is a brand-name version of semaglutide approved for Type 2 diabetes. EdenRx provides compounded semaglutide, a provider-reviewed equivalent formulated by licensed pharmacies — not FDA-approved under the same NDA as the brand.

How is it administered?

Semaglutide is administered via subcutaneous (under the skin) injection. Administration instructions are provided by the patient's assigned provider.

Is it available without insurance?

Yes. EdenRx programs are priced for out-of-pocket access and do not require insurance approval.

Provider Review Required: All treatment plans, doses, and eligibility determinations are made exclusively by licensed healthcare providers after individual medical review.

Semaglutide vs Tirzepatide — Quick Comparison

FeatureSemaglutideTirzepatide
MechanismGLP-1 receptor onlyGLP-1 + GIP dual receptor
Brand equivalentOzempic / WegovyMounjaro / Zepbound
AdministrationWeekly injectionWeekly injection
Starting priceFrom $149/monthFrom $229/month
Clinical evidenceExtensive — FDA approved 2017Newer — FDA approved 2022
Avg weight reduction (trials)~15% body weight~20%+ body weight
ContraindicationsMTC, MEN 2, pregnancyMTC, MEN 2, pregnancy

Ready to refer a candidate?

Direct interested individuals to the free medical assessment. Providers review every application.

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Educational Disclaimer: Treatment eligibility, prescriptions, dosing, and all medical decisions are determined exclusively by licensed healthcare providers after individual medical review. This content is for educational and informational purposes only and does not constitute medical advice.